After two thrilling weekends of NCAA Tournament matchups, the stage is officially set for the 2025 Final Four. What began with a field of 68 teams has now been narrowed down to just four contenders, setting the scene for what promises to be a historic weekend. For the first time since 2008, all four No. 1 seeds have advanced to the Final Four.
The action unfolds on Saturday, April 5, at the Alamodome in San Antonio, Texas, with the championship showdown scheduled for Monday, April 7. The first semifinal features Florida taking on Auburn at 6:09 p.m. ET, followed by a clash between Houston and Duke at 8:49 p.m. ET.
Let’s assess the all important March Madness Odds 2025.
Below are the odds from three of the best NCAAB Betting Sites.
| Final Four |  |  |  |
|---|---|---|---|
| Florida | -145 | -150 | -150 |
| Auburn | +125 | +130 | +129 |
| Florida -2.5 | -110 | -110 | -110 |
| Aubrun +2.5 | -110 | -110 | -110 |
| Over 160.5 | -110 | -110 | -110 |
| Under 160.5 | -110 | -110 | -110 |
Florida basketball delivered one of the most unforgettable comebacks in program history on Saturday night, rallying from a nine-point deficit in the final three minutes to take down No. 3 seed Texas Tech 84-79 in the Elite Eight. With the victory, the Gators punched their ticket to the Final Four for the sixth time in school history.
Thomas Haugh and Walter Clayton Jr. each buried a pair of clutch three-pointers, but Clayton’s second shot will be etched in UF history. Rather than opting for a simple game-tying layup, he stepped back and drilled a go-ahead three-pointer that sent Gator fans into a frenzy.
Down the stretch, Florida was flawless from the free-throw line, sinking all four of its attempts in the last three minutes. Meanwhile, Texas Tech’s top two players, Darrion Williams and JT Toppin, missed the front end of their one-and-one opportunities, proving costly in the final moments.
Up next, Florida will square off against the tournament’s No. 1 overall seed, Auburn, in the Final Four.
Auburn secured its spot with a hard-fought victory over Michigan State in the Elite Eight, despite star Johni Broome battling an elbow injury. However, concerns over Broome’s health have seemingly influenced oddsmakers, as the Tigers enter this game as underdogs and sit as the fourth favorite to win the championship.
These teams met once earlier this season at Auburn, where Florida came away with a nine-point win. Auburn also fell to Duke by six but managed to edge out Houston by five. With both squads capable of big performances, Saturday’s matchup has all the makings of a tightly contested battle.
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Below are the odds for the second of the final four match-ups.
| Final Four | | | |
|---|---|---|---|
| Houston | +200 | +220 | +218 |
| Duke | -240 | -260 | -260 |
| Houston +5.0 | -105 | -107 | -105 |
| Duke -5.0 | -115 | -113 | -115 |
| Over 136.5 | -110 | -110 | -110 |
| Under 136.5 | -110 | -110 | -110 |
The second showdown at the Alamodome on Saturday will showcase a highly anticipated battle between No. 1 seeds Duke and Houston. Both teams have put together remarkable runs to reach the Final Four, though they took different paths—Duke has dominated every opponent in the tournament, while Houston has had to go through the toughest possible competition at each stage.
Statistically, these two programs stand atop college basketball. The Blue Devils boast the nation’s best offensive efficiency, averaging 83.7 points per game, ranking them among the top 10 scoring teams in the country. Meanwhile, the Cougars anchor their success on defense, allowing just 58.3 points per contest—the lowest in the nation.
The key question heading into this matchup: Will Duke’s high-powered offense dictate the pace, or will Houston’s stifling defense prove too much to overcome? The answer will determine which team earns a spot in the national championship game.
I am backing Duke to get the job done in this Final Four match-up.
Below are the bets sports betting sites where you can place your NCAAB Final Four bets. You can read our reviews to help determine the best option for you.
About the Author
Henry began his journey in the betting industry before transitioning into a writing career. While his expertise lies in soccer, golf, and darts, he covers a wide range of sports from across the globe. Armed with a BA Honors degree in Business and Management, Henry climbed the ladder at William Hill in England. Beyond sports writing, he has also achieved success in the Property and Finance sectors, where he continues to be active. Now based in Barcelona, Henry enjoys the city’s vibrant sports culture and plays golf year-round as a member of the Real Federacion Espanola de Golf.
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