Marc Marquez Heavily Favored In Grand Prix of The Americas MotoGP Picks

Updated March 26, 2025
Updated March 26, 2025By Bob Duff

In the MotoGP picks, the early-season chase for the championship is turning into a family affair.

Leading the way through the first two races of the season is six-time champion Marc Marquez. The Spanish rider has been nothing short of dominant since switching this season to the factory Ducati Lenovo team.

Right behind him in the standings is his younger brother Alex Marquez. He’s also riding a Ducati for BK8 Gresini Racing.

Entering this week’s stop of the circuit, Sunday’s Grand Prix of The Americas, it’s the elder Marquez who oddsmakers strongly like to keep on winning. He’s set as the -400 odds-on favorite.

Alex Marquez is the second betting choice. He’s set with a line of +400.

Let’s look at the latest Grand Prix of The Americas MotoGP betting lines. Remember, odds are always subject to change.

Grand Prix Of The Americas OddsBovadaBetOnlineBetUS
Marc Marquez-400-400-400
Alex Marquez+450+450+450
Francesco Bagnaia+650+650+650
Fabio Di Giannantonio+1800+1800+1800
Franco Morbidelli+1800+1800+1800
Marco Bezzecchi+2500+2500+2500
Pedro Acosta+3300+3300+3300
Brad Binder+4000+4000+4000
Ai Ogura+5000+5000+5000
Alex Rins+5000+5000+5000
Johann Zarco+6600+6600+6600
Fabio Quartararo+8000+8000+8000
Joan Mir+10000+10000+10000
Jack Miller+15000+15000+15000
Enea Bastianini+30000+25000+25000
Luca Martini+30000+25000+25000

Two-time world champion Francesco Bagnaia is the next betting choice at +650. He’s the only other rider with odds shorter than +1800.

Six-Time Champ Dominating Early-Season MotoGP Picks

Marc Marquez has not only won both of the races on the slate so far this season, he’s captured pole position for both races. As well, he’s won the Saturday sprint each week.

In this season’s race, following Saturday qualifying will be the 10-lap sprint. The 20-lap main event race is set for Sunday at 3 p.m. EST around the 20-turn, 3.43-mile Circuit of The Americas layout. Remember, the race odds could be changing based upon the results of the qualifying round and the sprint race. That’s why it’s always wise to track the early outcomes. You’ll be able to see which riders are holding hot hands and are the best for you to bet.

Marc Marquez (-400)

The Spanish legend is coming in hot to a circuit that he has previously owned. Marc Marquez has won more Grand Prix of The Americas races (seven) than any other rider.

He also taken pole position for this race on a record seven occasions. Marquez finished second in last year’s race.

Alex Marquez (+800)

As is so often the case with little brother, Alex Marquez is second best. He’s finished second in both races this season.

The GP of The Americas has not been kind to him . The younger Marquez finished 15th last year. He was forced to retire from the race the two previous years. He finished 12th in 2021.

Francesco Bagnaia (+350)

The 2022 and 2023 world champion, Bagnaia also hasn’t enjoyed his GP of The Americas experience.

He’s only found the podium once. Bagnaia finished third in 2021.

Fabio Di Giannantonio (+1800)

Since a 2023 win at Qatar, Di Giannantonio has gone 21 races without a podium finish. He’s never finished better than sixth in the Grand Prix of The Americas.

Franco Morbidelli (+1800)

The Italian rider was fifth in this race in 2019. However, he’s not cracked the top 10 in the GP of The Americas since.

Latest MotoGP Championship Odds

Not surprinsingly, Marc Marquez is also the overwhelming choice in the MotoGP picks to win his seventh world title. It would also be his first since 2019.

At both Bovada and BetUS, Marc Marquez is the -1000 odds-on favorite. You’ll get a slightly better betting line at Betonline, which has Marquez at -800 odds.

Alex Marquez and Bagnaia are the co-second betting choice at +700. Alex Marquez has never won a world title. Bagnaia was MotoGP world champion in 2022 and 2023.

Reigning champ Jorge Martin is starting the season on the injured list. That’s caused his betting line to defend his title to soar to +6600.

Grand Prix Of The Americas MotoGP Picks Winner

At this juncture of the season, making a case for anyone but Marc Marquez winning this race is a daunting challenge. He’s seen the back of no rider at the finish line of any event so far this year. Putting the best rider on the circuit on the best equipment was expected to be a winning combination. That being said, no one likely anticipated it being this successful this quickly.

Marc MarquezTo win MotoGP Grand Prix of The Americas
-400
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Then when you factor how dominant the Spaniard has been over the years on this circuit, betting against Marc Marquez makes little sense. Go with him in the Grand Prix of The Americas MotoGP picks.

Additional Thoughts And Notes Regarding MotoGP Bets

Once you are all up to speed on the latest MotoGP Grand Prix of The Americas news and information, make sure to check out the fantastic array of resources for you over at SBS. Of course, for even more analysis on the topic covered here, you should bookmark the MotoGP betting sites rundown. On this page you can find a variety of awesome information as it relates to the sport including the latest betting markets and beyond. Additionally, for those on the go, another fantastic page to familiarize yourself with is the best betting apps breakdown, which goes over all of the nuances of mobile betting sites and beyond. Finally, for those interested in maximizing their wagers, look no further than the best bonus betting sites guide, which contains a catalog of the latest and greatest welcome bonus offers. 

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Summary
Marc Marquez Heavily Favored In GP of The Americas MotoGP Picks
Article Name
Marc Marquez Heavily Favored In GP of The Americas MotoGP Picks
Description
Marc Marquez has won both races so far on the 2025 MotoGP schedule and is the -400 odds-on favorite to win the Grand Prix of the Americas.
Author
Publisher Name
Visca Web

About the Author

Bob Duff
Bob Duff

Theo is our NFL guy. He is the go-to man for all things football and has proven himself to be one of the most expansive writers here, with a broad knowledge of North American sports. He's a veteran journalist based in Ontario, and has covered the gambling and sports betting industry since 2016. He has written more than two dozen books and covered the NFL since the early 1990s.

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